A defined patient group
The OSA indication applies to adults with obesity and moderate-to-severe obstructive sleep apnea.
Please fill out the form below and we will get back to you as soon as possible.
For people with obesity and obstructive sleep apnea, medically supervised weight management may help improve sleep, breathing, and overall health.
Weight and obstructive sleep apnea are closely linked. Extra tissue around the neck and upper airway can make the airway more likely to narrow or collapse during sleep.
For some people, losing weight can meaningfully reduce the severity of sleep apnea. Addressing weight may therefore be an important part of care alongside other treatments.
At Houston Sleep Health, we consider your sleep, weight, metabolic health, lifestyle, and other medical conditions when discussing your treatment plan.
Discuss your sleep healthGLP-1–based medicines can help eligible patients manage obesity and related health conditions. Some medicines, including tirzepatide, act on both GLP-1 and GIP pathways.
These treatments can reduce appetite and help you feel fuller. When combined with appropriate nutrition and physical activity, they may support meaningful weight loss.
Medication selection requires an individual evaluation. Your clinician will discuss potential benefits, side effects, and whether treatment is suitable for your health history.
In December 2024, the FDA approved Zepbound (tirzepatide) for adults with obesity and moderate-to-severe obstructive sleep apnea, used with a reduced-calorie diet and increased physical activity. It was the first medication approved specifically for OSA.
In clinical trials involving this patient population, tirzepatide reduced breathing interruptions during sleep more than placebo.
The OSA indication applies to adults with obesity and moderate-to-severe obstructive sleep apnea.
Treatment is used alongside a reduced-calorie diet and increased physical activity.
Your clinician assesses suitability and monitors your response, tolerability, and sleep health.
This approval is specific to Zepbound and its labeled use; it does not mean every GLP-1 medication is approved to treat sleep apnea.
Read the FDA announcementThese factors may prompt a discussion about medically supervised weight management. They do not establish eligibility on their own.
Our clinicians review your medical history, current medicines, weight, sleep apnea severity, and other relevant factors before recommending treatment.
Explore your eligibilityWeight-loss medication does not replace every sleep apnea treatment. Many patients still need PAP therapy, an oral appliance, or another approach during weight loss and afterward.
Your individual plan may combine:
Support weight-related health goals while continuing prescribed airway support during sleep.
Learn moreFor suitable patients, a custom appliance may be used as part of a coordinated treatment plan.
Learn moreNutrition, physical activity, and ongoing support remain part of an individualized approach.
Learn moreSome patients may need less additional treatment over time, but sleep apnea should be objectively reassessed when appropriate. Continue your prescribed treatment until your clinician recommends a change.
At Houston Sleep Health, we look at how sleep, weight, metabolic health, energy, and overall health relate to one another.
Progress in one area may support improvements in another. Our goal is a plan that addresses your sleep apnea while helping you work toward sustainable improvements in your health.
From your first evaluation to ongoing monitoring, your care is guided by your medical needs and treatment response.
Schedule an evaluationWe review your sleep history, weight, medical conditions, medications, and previous attempts to lose weight.
Your clinician assesses whether a GLP-1/GIP-based medicine or a different approach is appropriate.
Medication, nutrition, physical activity, sleep apnea treatment, and follow-up are coordinated as needed.
We monitor weight, treatment response, side effects, and overall health as your care progresses.
As your weight and health change, your clinician reassesses whether your sleep apnea treatment needs to change.
Understand how medically supervised weight management may fit into your sleep apnea care.
Ask our teamExcess tissue around the upper airway can contribute to airway narrowing during sleep. For some patients, weight loss improves OSA severity. Your response needs to be assessed individually.
No. The December 2024 FDA approval described here applies specifically to Zepbound (tirzepatide) for moderate-to-severe OSA in adults with obesity, together with a reduced-calorie diet and increased physical activity.
Your clinician reviews your weight, diagnosis, OSA severity, health history, current medicines, and treatment goals. Medication is not suitable for everyone, and a consultation is needed to assess your options.
Do not stop prescribed CPAP or another sleep apnea treatment on your own. Many patients continue sleep therapy during and after weight loss. Your clinician can reassess your OSA and advise whether changes are appropriate.
Yes. Medication is one part of care. Your plan may coordinate nutrition, physical activity, sleep treatment, and follow-up according to your needs.
Your care team monitors weight, response to treatment, side effects, and overall health. Your sleep apnea treatment may also be reassessed as your health changes.
Not necessarily. Some patients have meaningful improvement, while others continue to need CPAP, an oral appliance, or another treatment. Objective reassessment helps guide decisions rather than assuming OSA has resolved.
Let’s care for both. If you have sleep apnea and are struggling with your weight, Houston Sleep Health can help you explore whether medically supervised weight management could be part of your plan.